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prednisone/bloating

Question:

If prednisone is suppose to be an anti-inflammatory why is it when your on it you bloat up like a balloon? isn’t it suppose to ease the inflamed area? Never understood this. I was on it once and really don’t want to be on it again!! Mary/az

Response:

Prednisone is a steroid. Mary Speiser <maryspe…@yahoo.com> wrote in message

news:39218AE8.7550D141@yahoo.com… – Hide quoted text — Show quoted text -> If prednisone is suppose to be an anti-inflammatory why is > it when your on it you bloat up like a balloon? isn’t it > suppose to ease the inflamed area? Never understood this. I > was on it once and really don’t want to be on it again!! > Mary/az

Response:

On Wed, 17 May 2000 20:24:31 +1200, "Vic" <v…@ezysurf.co.nz> wrote: >Prednisone is a steroid.

"bloating" isn’t the same thing as inflammation.  Prednisone actually causes damage to the stomach muscles … let me go grab the Hamline post regarding this… The following explains at least part of the bloating problem caused by prednisone.  Initial bloating is probably due to the stomach acid increase caused by prednisone.  Extra stomach acid -> extra gas -> bloating. HTH – Hide quoted text — Show quoted text ->>so I look as if I’m carrying a 10-month baby. There >>must be a common explanation for this. The body shape >>is similar to Cushing’s. >And this is indeed the expalanation. >Glucocorticoids (like prednisone) cause atrophy of muscles by two major actions: >1. Enhancing degradation of components in the muscle cells. >2. Suppressing adrenal activity and therefore reducing plasma DHEA. DHEA is >a steroid secreted by the adrenal, concomitantly with the natural >glucocorticoids, in order to protect the muscles from the deleterious >effects of the latters. >The first set of muscles to be destroyed when muscle degradation takes >place, are those of the abdominal wall. Similar to glucocorticoids, hunger >also consume the muscles of the abdominal wall, first. >When there are not enough muscles to hold the guts tight to the back, the >weight of the guts pushes the abdominal wall forward as it is hanging mostly >on the skin now, giving the impression of a swollen abdomen, like seen in >femine areas too, as hunger also cause these. >The pressure on the abdoimnal wall on one hand and the reduction in skin >thickness on the other, causes some tearing of deep skin tissues and we can >see what had left from the muscles, through the cracks in the deep skin, >these are the dark strips (facias) that apears on the sides of the abdomen. >So yes, it is very similar to Cushing syndrome, actually it is aquired >Cushing syndrome, caused by the prednisone taken.

Response:

KC, I’ve often heard you speak of the Hamline group, so I have tried going there.  I get the home page, but I never have found the place where you can post and see message threads.  Must be the cerebritis! :0)   Can you help me find my way to the site? Thanks muchly, Barbara

Response:

  Hamline Lupus Page (Excellent references)   http://www.hamline.edu/lupus/index.html  (click on USENET)

Response:

Sandra, I feel like this is an intelligence test and I am failing! :0)  When I click on usenet on the Hamline home page it comes right back here.  I double click, I single click, I bang the computer, and whatever, this newsgroup appears. Help again please… Barbara SCroyle909 <scroyle…@aol.com> wrote in message

news:20000517222415.23669.00003209@ng-ce1.aol.com… – Hide quoted text — Show quoted text ->   Hamline Lupus Page (Excellent references) >   http://www.hamline.edu/lupus/index.html  (click on USENET)

Response:

In article <6kd5isc3476cjl5s63e2hf11i116ajg…@4ax.com>, KC  <kcdoc…@ghg.net> wrote: >On Wed, 17 May 2000 20:24:31 +1200, "Vic" <v…@ezysurf.co.nz> wrote: >>Prednisone is a steroid. >"bloating" isn’t the same thing as inflammation.  Prednisone actually >causes damage to the stomach muscles … let me go grab the Hamline >post regarding this…

Actually, the _immediate_ reason for bloating while on steroids is water retention.  Steroids are pretty close to the hormonal messengers your body already uses, and it tells your kidneys to retain more water, and dump potassium and calcium.  This is why salt is a no-no on steroids, because the kidneys keep sodium and potassium in equilibrium.  Take in a lot of sodium, the kidneys will start dumping potassium.   Shorter, less easily understood answer:  steroids mess with vasopressin levels, causing water retention. — Lee M.Thompson-Herbert        KD6WUR                  l…@gw.retro.com Member, Knights of Xenu (1995).  Chaos Monger and Jill of All Trades. "There are some people who will argue whether the flames are blue or green, when the real question is that their arse is on fire."

Response:

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